Detection of RNA outliers Pipeline

Aberrant Expression Module

Go to the Counting tab and click on Datasets.R. Then, select the desired analysis group. It contains different plots like the number of reads counted, size factors, expression of each gene in FPKM and the number of expressed genes.

Go to the Outrider tab and click on Datasets.R. Then, select the desired analysis group. It contains different plots like the steps towards finding the optimal encoding dimension, heatmaps of the sample covariation before and after correction, biological coefficient of variation; and tables containing aberrant samples and results table.

Expression outliers are computed using OUTRIDER (Brechtmann, Mertes et al., AJHG, 2018).